Joseph Porrovecchio

Over the past 3 years I have been on various dosages of Prednisone
(http://www.drugs.com/search.php?searchterm=Mestinon&is_main_search=1) and Mestinon (http://www.drugs.com/prednisone.html) to manage the various symptoms of Myesthenia Gravis.

For about 1 year, post thymectomy, I was relatively symptom free and required a low dose of Predisone and Mestinon. It was really quite amazing, the thymectomy had reduced my Predisone intake from 60mg to 5mg and Mestinon from 12 x 60mg to 4 x 60mg.

Myesthenia is a disease which can go into , or come out of, remission of symptoms without warning .
Well, after about a year my symptoms returned – focused in the bulbar area – the neck, mouth, eye and throat area.
So, my Neurologist increased the dosages accordingly – my symptoms started to get better for about 6 months, at which point we decide start to decrease medications. Again, symptoms remained stable for about 3 months but them flared up again.

It is because of the relatively unreliable effect of Prednisone and Mestinon that the decision to shift to the immuno suppresant IMURAN was made by my Neurologist (http://www.drugs.com/search.php?searchterm=Imuran&is_main_search=1)